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These 10 Biohacking Supplements Impressed Us with Results
Jan 20, 23
Tags: Usage
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Author: Sony Sherpa

These 10 Biohacking Supplements Impressed Us with Results

  • by Sony Sherpa

    Medically reviewed by

    Sony Sherpa

    Dr. Sony Sherpa is a board-certified Clinical Doctor and dedicated advocate for holistic medicine, specializing in functional mushrooms. Her blend of medical expertise and passion for alternative wellness lends authenticity to her role as a contributor for Natures Rise.

  • |
  • 23 min read
These 10 Biohacking Supplements Impressed Us with Results

Biohacking supplements are specially formulated substances that enhance various aspects of health and well-being. These supplements align with biohacking principles—the practice of changing our chemistry and physiology to maximize body and brain performance. Common biohacking supplements include nootropics for cognitive enhancement, nutritional supplements for physical health, and sleep aids for improved sleep quality.

Examples include Omega-3 Fatty Acids for heart health and brain function, B-Complex Vitamins for energy and cellular metabolism, magnesium for stress reduction and sleep improvement, Vitamin D for immune support, Probiotics for gut health, Curcumin for inflammation reduction, and Resveratrol for anti-aging benefits.

Ginseng can also boost cognitive function, reduce inflammation, and improve overall well-being. Zinc is necessary for immune function and is vital in protein synthesis and DNA repair. Zinc also has anti-inflammatory properties and may help reduce the risk of certain diseases.

Lion's mane mushroom and cordyceps mushroom are two other supplements worth considering. Lion's mane improves cognitive function and reduces symptoms of anxiety and depression. On the other hand, Cordyceps enhances physical performance by increasing oxygen uptake and improving endurance. 

This article will explore the ten most effective biohacking supplements backed by scientific research. Whether you're a seasoned biohacker or just getting started, these supplements may help you take your health and performance to the next level.

Unlocking Human Potential: Unraveling the Concept of Biohacking

Unlocking Human Potential: Unraveling the Concept of Biohacking

Biohacking, in essence, is the practice of manipulating the human body's natural systems to achieve improved health and wellness. Biohacking is all about understanding and leveraging the intricate biological processes within our bodies to enhance physical, cognitive, and overall well-being.

Different Forms of Biohacking: A Spectrum of Health Opportunities

Biohacking comes in various forms, each focusing on different aspects of health and wellness. As a result, it's a broad concept encompassing numerous techniques and strategies, four of which we'll delve into more deeply.

Nutrigenomics: Food as a Pathway to Enhanced Health

The first form of biohacking is nutrigenomics, which studies how different foods interact with our genes. This area of biohacking emphasizes that what we consume can profoundly impact our overall health. By taking supplements orally, for instance, biohackers aim to leverage these life-changing health benefits by optimizing nutrient intake for their unique genetic makeup.

Sleep Optimization: Recharging for Improved Health

Sleep optimization is another popular form of biohacking. It involves adjusting various factors, such as environment and routine, to improve sleep quality and promote better health and wellness. Strategies here may include everything from creating a conducive sleep environment to using specialized sleep aids.

Physical Biohacks: Amplifying Blood Flow and Beyond

Physical bio hacks are often centered around improving physical health parameters like blood flow and strength. Techniques used in this realm can range from high-intensity interval training (HIIT) exercises designed to improve blood flow and heart health to cold therapy, which relieves symptoms of various conditions and further enhances blood flow.

Mental Biohacks: Boosting Brain Power

Mental bio hacks focus on cognitive health. Techniques here can involve meditation for stress relief or nootropics. Nootropics can enhance cognitive function, mainly executive functions such as memory, creativity, and motivation.

The Scientific Backbone: Understanding the Science Behind Biohacking

While biohacking might sound like something from a sci-fi movie, it's firmly rooted in scientific principles. The science of biohacking involves a deep understanding of the body's biological processes and the means to manipulate them positively. 

Biohacking blends traditional wisdom and modern science, from knowledge of human physiology and genetics to advanced technology that monitors health parameters. This intersection makes biohacking a promising field for achieving improved health and wellness on a highly personalized level.

Best Biohacking Supplements: Your Health Enhancers

Best Biohacking Supplements: Your Health Enhancers

Biohacking supplements are specially designed products that deliver nutrients and active components to the body to promote optimal health and wellness. The fundamental idea is to offer a high-quality product that supports the body's natural functions and offers a significant health boost, much like a personal healthcare provider in a bottle.

A Spectrum of Supplements: Catering to Varied Needs

Health supplements come in various forms, each designed to target a specific area of health. From cognitive enhancement to physical health improvement, these supplements work with your body's natural mechanisms to promote well-being.

Nootropics: Supplements for an Enhanced Mind

Nootropics, often called 'smart drugs,' are designed to enhance cognitive function. They can help to improve memory, creativity, and motivation and even help with cognitive impairment. Certain nootropics, such as mushroom supplements, have been recognized for their potential to boost brain health and cognitive function.

Nutritional Supplements: Elevating Your Physical Health

These supplements are designed to deliver essential nutrients that may be lacking in your diet. They can help to carry vitamins, minerals, and proteins throughout the body, promoting overall health

Some, like protein powder, can assist those aiming to lose fat and gain muscle. Others might target specific health conditions, such as congestive heart failure, by improving the function of blood vessels and promoting better circulation.

Sleep Aids: For the Beauty of Restful Sleep

Quality sleep is a cornerstone of good health, and various biohacking supplements are designed to promote restful, rejuvenating sleep. These supplements can range from melatonin to magnesium, each working uniquely to aid sleep quality and duration.

Top 10 Best Biohacking Supplements For Boosting Health

1. Ginseng


Research has shown that(1) ginseng enhances cognitive function, including memory, attention, and concentration. Moreover, research conducted in 2018(2) showed that ginseng reduces inflammation, reducing the risk of chronic diseases like cardiovascular disease, diabetes, and cancer. 

Interesting Read: See how Chaga mushroom fights cancer.

Additionally, research has confirmed that(3) it boosts immune function by stimulating the production of natural killer cells and other immune cells, improving the body's ability to fight infections and diseases.Finally, it has anti-anxiety properties and can reduce symptoms of stress and anxiety by regulating cortisol levels and promoting relaxation.

2. Zinc


Zinc has numerous health benefits, including improved immune health and reduced inflammation in the human body. The unique mineral also supports cognitive function, sleep, and hormonal balance. 

Interesting Read: See the best mushrooms for hormonal balance.

Research has shown that(4) zinc is essential for developing and activating immune cells. In addition, it has anti-inflammatory properties that fight chronic diseases. 

A research study conducted in 2022 verified that(5) zinc also plays a vital role in brain function. Furthermore, research has found(6) that zinc improves sleep quality by regulating the melatonin hormone, particularly in older adults. Zinc is also essential for producing and regulating hormones like testosterone and insulin, promoting hormonal balance. 

3. Lion's Mane Mushroom

Lion's Mane Mushroom

Lion's mane contains compounds that stimulate the growth and repair of nerve cells(7), leading to improved cognitive function, including memory, learning, and overall brain health.This is one of the reasons these brain enhancers are often called "smart mushrooms" or "smart drugs," although they are fungi and not a type of drug. 

Lion's Mane mushrooms also have anti-inflammatory properties that can help reduce inflammation. In addition, Lion's Mane fights anxiety and depression. 

Furthermore, this biohacking supplement also has immune-boosting properties. In addition, its prebiotic fiber content can promote the growth of healthy gut bacteria, leading to improved digestion and overall gut health. 

Interesting Read: See the best mushrooms for gut health.

4. Cordyceps Mushroom

Cordyceps Mushroom

Well-known fungi in traditional Chinese medicine, Cordyceps mushrooms(8), improve athletic performance and endurance by increasing oxygen uptake and energy production.For this reason, it is common for bodybuilders and athletes to use cordyceps pre-workout to enhance energy levels and strength and fight fatigue. 

Because of their ability to fight fatigue, cordyceps are often considered some of the best wakefulness enhancers. This biohacking supplement provides a natural energy boost and allows you to crush your day after getting out of bed.

Research has shown that(9) cordyceps contain bioactive ingredients and compounds that stimulate the immune system, leading to increased immune function and better overall health. Cordyceps mushrooms also contain antioxidants that can help reduce oxidative stress and prevent cellular damage, leading to anti-aging effects. 

Furthermore, their anti-inflammatory properties can reduce the risk of chronic diseases. Moreover, research(10) has proven that Cordyceps mushrooms boost libido, with their aphrodisiac effects improving sexual function in both men and women. 

5. Vitamin D

Vitamin D

Research has confirmed(11) that vitamin D is necessary for calcium absorption, essential for bone health. In addition, it helps prevent osteoporosis, a condition that weakens bones. 

Research has linked(12) Vitamin D deficiency to an increased risk of chronic diseases such as heart disease, diabetes, and certain cancers. Moreover, adequate levels of Vitamin D can help improve mood and reduce depression symptoms by regulating the production of serotonin—this makes vitamin D an effective supplement for boosting mental health.

Vitamin D is also essential for brain function, improving cognitive function. In addition, vitamin D also boosts the immune system, helping fight off infections and diseases. 

You can find vitamin D in mushrooms and other foods. However, the most popular way of getting vitamin D is sunlight exposure.

6. Vitamin C Supplements

Vitamin C Supplements

Vitamin C boasts robust antioxidant properties, protecting you from oxidative stress associated with cellular damage and aging. Research has also shown that(13) Vitamin C is crucial for immune function, as it helps the body fight off infections and diseases. 

Moreover, research indicates(14) that vitamin C is necessary to produce collagen. This protein provides structure to the body's skin, bones, and other tissues, boosting skin health. 

Moreover, vitamin C supplements reduce the risk of chronic diseases, including stroke, cancer, and heart disease. The vitamin also helps the body absorb iron, essential for producing red blood cells and oxygen transport. 

7. Omega 3 Fatty Acid

Omega 3 Fatty Acid

Research has shown that(15) omega-3 fatty acids, primarily found in fish oil, improve heart health by lowering blood pressure, reducing triglycerides, and preventing the formation of blood clots.Moreover, omega-3 fatty acids are anti-inflammatory, treating rheumatoid arthritis, asthma, and inflammatory bowel disease. 

Research indicates that(16) Omega-3 fatty acids are also essential for brain function, improving cognitive function, memory, and mood. Moreover, these fatty acids fight age-related macular degeneration, a leading cause of blindness in older adults. Some studies have also suggested(17) that fatty acids may reduce the risk of certain cancers, such as colon, breast, and prostate cancer. 

8. Probiotics


Probiotics are an excellent biohacking supplement because they support gut health and overall immunity.They help maintain a healthy balance of gut bacteria, which is essential for proper digestion and absorption of nutrients. Probiotics can help you lose weight and normalize bowel movements, especially when taking fiber supplements. 

The gut is home to approximately 70% of the body's immune system. Therefore, probiotics' ability to support a healthy balance of gut bacteria can help to support immune function. 

9. Magnesium


Magnesium is involved in many processes in the body, including muscle and nerve function, energy production, and bone health. As a result, this supplement boosts mental and physical performance, helps reduce mental fatigue, and guarantees improved health. 

Research has shown that(18) it supports relaxation and reduces stress. Magnesium helps to regulate the production of cortisol, the stress hormone. It also helps to relax muscles and promote feelings of calmness and relaxation. This can help reduce anxiety symptoms and promote better sleep, making magnesium supplements one of the best sleep aid.

Studies have shown(19) that magnesium can help to lower blood pressure, reduce inflammation, and improve blood sugar levels. This can help increase cardiovascular health and enhance healthy blood flow. Magnesium also supports bone health by balancing calcium and other minerals, reducing the risk of osteoporosis.

10. Bacopa Monnieri

Bacopa Monnieri

Research has shown(20) that Bacopa Monnieri may improve cognitive function and memory retention. Studies have also shown that(21) it may help to protect the brain from oxidative stress, inflammation, and other forms of damage. This can promote healthy brain function and reduce the risk of Alzheimer's and Parkinson's.

Read More: See how Lion's mane fights Parkinson's disease.

Building a Biohacking Regimen: Incorporating Supplements into Your Routine

Building a Biohacking Regimen: Incorporating Supplements into Your Routine

Creating a personalized biohacking routine with supplements requires careful thought and planning. It is crucial to understand your health needs, the safety of the supplements you're considering, and the strategies for maximizing their benefits.

Determining Your Ideal Supplements: A Step-by-Step Guide

Here are some steps to help you figure out which supplements will best serve your biohacking goals:

Step #1: Understand Your Needs

Start by assessing your health goals and needs. This could include improving cognitive function, supporting physical performance, or enhancing sleep quality.

Step #2: Do Your Research

Once you've determined your goals, research which supplements align with them—each supplement has unique benefits, so understanding its effects is crucial.

Step #3: Consult a Healthcare Provider

Before incorporating any supplement into your regimen, consult a healthcare provider. They can provide guidance based on your specific health condition and needs.

Step #4: Quality Over Quantity

Always opt for high-quality, reputable supplements. Cheaper alternatives might not offer the same benefits and could contain harmful substances.

Prioritizing Safety: Ensuring Safe Use of Health Supplements

Like any health-related product, safety is paramount when using dietary supplements. Here are a few essential tips to ensure safe use:

Follow Dosage Guidelines

Always adhere to the recommended dosage provided on the supplement packaging. Overconsumption can lead to adverse effects.

Track Your Response

Monitor how your body responds to the supplements. If you experience any adverse effects, stop using and consult a healthcare provider.

Be Aware of Interactions

Some supplements can interact with other medications or substances. Ensure you're aware of these potential interactions to prevent any harmful effects.

Unleashing Full Potential: Strategies for Maximizing Supplement Benefits

To make the most out of your biohacking and dietary supplements, consider these strategies:

  • Combine with a Healthy Lifestyle: Health supplements work best with a healthy lifestyle, including a balanced diet, regular exercise, and adequate sleep.
  • Stay Consistent: Consistency is vital in seeing the benefits of supplements. So make them a regular part of your routine.
  • Be Patient: Most supplements don't offer immediate results. It often takes time to notice changes, so be patient and give the supplements time to work.

Incorporating supplements into your routine is an exciting step towards enhanced health and wellness. However, remember to choose wisely, prioritize safety, and be patient to see the fruits of your biohacking efforts.

Biohacking Supplements: Navigating the Controversy

Biohacking Supplements: Navigating the Controversy

While supplements appeal to many, it's essential to acknowledge the controversies and debates surrounding their use. These issues range from potential risks and concerns to regulatory issues and effectiveness debates.

Potential Pitfalls: Risks and Concerns

Supplements, like any health product, come with possible risks and concerns. These include:

  • Adverse Effects: Some supplements can cause unwanted side effects, especially if taken in excessive amounts or combined with certain medications.
  • Quality and Purity: There is a risk of contamination with substances not listed on the label due to inconsistent manufacturing processes.
  • Underlying Health Conditions: People with certain health conditions may react adversely to some supplements. Always consult a healthcare provider before starting a new supplement regimen.

The Regulatory Maze: Issues Surrounding Health Supplements

Regulatory issues are another point of controversy in the world of health supplements. Unlike prescription drugs, dietary supplements are not required to be proven safe or effective before selling, raising potential quality and safety issues. Moreover, the industry is notorious for its lack of transparency, making it hard for consumers to verify the claims made about a product's benefits.

Measuring Up: The Debate on Effectiveness

The effectiveness of supplements is a hotly debated topic. Some argue that while enhancing one's biology sounds appealing, the evidence supporting the effectiveness of many biohacking supplements is either scant or inconclusive.

Others point out that the effectiveness of biohacking and health supplements may vary significantly among individuals due to genetic differences. What works for one person might not work for another, highlighting the need for a personalized approach to biohacking.

Despite these controversies, the popularity of biohacking supplements continues to rise. As with any health-related decision, it is essential to do thorough research, consult with healthcare professionals, and consider individual health needs and goals when exploring the world of biohacking supplements.

FAQs About Biohacking Supplements

How Do You Start Biohacking?

The first step in biohacking is to define your goals and identify the specific areas you want to focus on. Educating yourself on the latest research and techniques in the field is essential to ensure that you are using safe and effective strategies. Before diving into advanced biohacking techniques, focus on the basics, such as eating a healthy diet, getting enough sleep, and exercising regularly.

Once the basics are in place, you can experiment with different biohacking techniques like supplements or practices such as intermittent fasting or cold exposure. It's crucial to keep track of your daily routine progresses. Next, monitor your biohacking interventions and track any changes in your health or performance. 

What Is A Biohacking Diet?

A biohacking diet is a personalized nutrition plan that uses food as a tool to optimize physical and mental performance, reduce inflammation, and improve overall health. A biohacking diet focuses on nutrient-dense foods that support the body's natural detoxification systems, reduce oxidative stress, and provide sustained energy throughout the day.

One common approach to biohacking the diet is to follow a whole-foods, plant-based diet that includes a variety of fruits, vegetables, whole grains, legumes, and healthy fats. These foods are rich in antioxidants, fiber, vitamins, and minerals that help to reduce inflammation and support cellular health. Some people may also consider taking protein supplements rich in naturally occurring amino acid. Adding essential amino acids to your daily routine can help you boost your overall health. 

What Are The Cons Of Biohacking?

Biohacking has the potential to improve health and performance, but it is not without its potential risks and drawbacks. Safety concerns are a significant issue, as many biohacking interventions, such as supplements, fasting, or cold exposure, can have potential risks if not done correctly or under the supervision of a healthcare professional. 

False claims by some companies or influencers about the benefits of certain interventions also contribute to the cons of biohacking. The biohacking industry is largely unregulated, making it essential to do thorough research and be wary of any claims that sound too good to be true.

Key Takeaways

Biohacking supplements can help you enhance mental function, improve energy and immunity, and combat infections. But the best biohacking benefits come from being well-informed and cautious about what works for your body. Talk to your doctor first to avoid side effects while using biohacking supplements. Then, the doctor will help you determine which supplements will work for you and which won't. 

Some of the best supplements to add to your lifestyle and wellness routine include mushrooms like Lion's mane and cordyceps, vitamins like D and C, herbs like bacopa monnieri and ginseng, probiotics, and fatty acids. These supplements will elevate your mind, improve your quality of life, boost your vitality, and make you a better person overall. To take things a step further, consider eating a healthy, balanced diet made of superfoods that contain enough proteins with branched-chain amino acids, vitamins, and all the minerals your body needs. 

Do you use biohacking or any other dietary supplements? Which is your favorite biohacking supplement right now? Please share with us in the comment section.

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  1. Cognition enhancing effect of panax ginseng in Korean volunteers with mild cognitive impairment: a randomized, double-blind, placebo-controlled clinical trial, (1) 
  2. Anti-Inflammatory Activity of Rg3-Enriched Korean Red Ginseng Extract in Murine Model of Sepsis, (2) 
  3. Ginseng, the 'Immunity Boost': The Effects of Panax ginseng on Immune System, (3) 
  4. Zinc as a Gatekeeper of Immune Function, (4) 
  5. Zinc in Cognitive Impairment and Aging, (5) 
  6. Dietary Zinc Acts as a Sleep Modulator, (6) 
  7. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia, (7) 
  8. Cordycepin for Health and Well-being: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential, (8) 
  9. Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials, (9) 
  10. A study of the aphrodisiac properties of Cordyceps militaris in streptozotocin-induced diabetic male rats, (10) 
  11. Vitamin D supplementation increases calcium absorption without a threshold effect , (11) 
  12. Vitamin D and Chronic Diseases, (12) 
  13. Vitamin C and Immune Function, (13) 
  14. Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review, (14) 
  15. Omega-3 fatty acids and cardiovascular disease, (15) 
  16. Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review, (16) 
  17. Protective Effects of Omega-3 Fatty Acids in Cancer-Related Complications, (17) 
  18. Magnesium Status and Stress: The Vicious Circle Concept Revisited, (18) 
  19. The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials, (19) 
  20. The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults, (20) 
  21. Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain, (21)

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