< class="article__title title"> Lion’s Mane Pre Workout: The Benefits and Scientific Evidence>
Lion’s Mane Pre Workout: The Benefits and Scientific Evidence
Jan 07, 22
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Author: Sony Sherpa

Lion’s Mane Pre Workout: The Benefits and Scientific Evidence


Lion’s mane mushroom is used as a culinary delicacy in many East-Asian cuisines. Apart from its delicious lobster-like taste, the mushroom has also attracted further attention due to its medicinal benefits. It has immune-boosting, anti-inflammatory, and anti-oxidant properties. Lion’s mane mushroom also improves overall cognitive function.

Fitness aficionados enjoy Lion’s mane pre workout. The demand for the mushroom, especially for improving athletic performance, has sky-rocketed over the recent years. If you are new to using Lions mane preworkout, you may have queries like are the mushroom's products and supplements good for workouts? Or is Lion’s mane a stimulant? 

This article will help you understand the benefits of Lion’s mane pre workout and give you insights on when and how to take the mushroom to promote athletic health.

Why Use Lion's Mane Pre Workout?

Lion’s mane mushroom is packed with beneficial beta-glucan polysaccharides, proteins, lectins, lipids, and active compounds like terpenoids, hericenone, and erinacine. 

When using Lions mane pre workout, these bioactive elements are associated with key benefits like reduction in fatigue and boosting energy. What's more, using Lion's mane in pre workout enhances concentration and reduces recovery time and inflammation. This would translate into a greater intensity of the workouts and an improved connection between the muscles and the mind.  

For people going to the gym to work on their BMI, the Lion's mane weight loss benefits also come in handy. The functional mushroom accelerates the metabolism of fat.

Using pre workout Lion's mane gives the body access to beta-glucans and digestive enzymes which have immune-boosting properties. A strong immune system helps the training athletes in recovery and helps in protecting the body against harmful bacteria and viruses.

What Are The Performance Benefits Of Lion’s Mane?

What Are The Performance Benefits Of Lion’s Mane?

The benefits of Lion’s mane on athletic performance have been backed scientifically. Research shows that people who use Lion's mane mushrooms pre-workout enjoy Lion's mane fatigue benefits and mushroom muscle growth benefits. 

In research study performed on mice(1), there was a significant increase in muscle endurance and improved muscle fatigue when the diet was supplemented with the functional mushroom. The mice were fed with 5% (w/w) of freeze-dried Lion’s mane for 24 hours. A substantial increment in muscle endurance was seen during exercise. The diet was supplemented with Lion’s mane mushroom for 8 weeks. No alterations in the muscle composition were seen between the study groups.

Another research study determined that when you pre workout with Lion's mane, you won't get tired quickly. The anti-fatigue activity of the mushroom was demonstrated in a case-control study on mouse models(2)

The study determined that the Lion's mane fatigue benefits come up when the multi-faceted fungus increases the glycogen content and antioxidants while reducing the lactic acid levels in the blood. It is also associated with a decrease in urea nitrogen and malondialdehyde which are the key markers of fatigue. The Lion's mane nitric oxide lowering benefits also play a key role in reducing fatigue when one is working out. 

In the Lion pre workout research study, the study group received the mushroom polysaccharide in dosages of 50, 100, and 200 mg/kg for 28 days while the other group received saline. Both groups were subjected to a forced swimming test. The results suggested that Lion’s mane mushroom has significant anti-fatigue properties. 

Researchers have indicated that using Lion's mane mushroom pre workout offers a potent fat-lowering property. A four-week study(3) performed on mice lowered blood cholesterol and body-weight gain. Improvement in fat metabolism is beneficial for enhancing endurance in athletes. What's more among the Lion mane benefits is that the ingredientsthe vitamins, minerals, and active compoundsin the mushroom also reduce the number of inflammatory substances released by fat tissue. 

Studies have shown(4) that Lion’s mane offers brain health benefits. Improving blood flow and bringing more oxygen to the brain, the mushroom improves focus, mental clarity, and concentration which play a vital role in enhancing athletic performance. This nootropic mushroom also stimulates the Nerve Growth Factor (NGF), which in turn enhances the growth and survival of neurons.

The anti-inflammatory property of the Lion’s mane plays a beneficial role in recovery from oxidative-stress-related tissue damage. The mushroom reduces inflammation associated with physical fatigue by decreasing the levels of Reactive Oxygen Species (ROS)(5). Excessive ROS leads to impaired muscle contractility, muscle fatigue, and increased muscle recovery time following injury. The study also noted that intake of this mushroom increased the levels of antioxidant enzymes like catalase and glutathione.

When And How To Take Lion’s Mane?

One of the most commonly asked questions is "can you take Lion's mane everyday?" This question often comes from people who are often worried that the ingredients in Lion's mane may become harmful if the super-food is taken daily. The answer to this question is yes, you can use Lion's mane mushrooms daily. If you work out every day, you can use Lions mane pre workout before each workout session. 

The only thing you will need to watch is theLion’s mane dosage . A good dosage should help you enjoy the Lion’s mane pre workout benefits without risking the minimal side effects that have been reported. 

When it comes to the best time to take Lion's mane pre workout, you are free to choose a schedule that works best for you. For example, if you work out in the morning, you can take Lion's mane mushrooms before exercise. The same case applies to people who work out in the evening. 

Lion’s mane mushroom can be enjoyed raw, tossed in your favorite meal, or used as a supplement. The best way to take Lion mane preworkout is in its powdered form, which is mixed with your favorite protein shake or smoothies. 

The powdered superfood fungus should be used once daily for the initial two weeks and later increased to two teaspoons per day. Using this dose of mushroom during pre workouts is not associated with any harmful effects.

Is Lion’s Mane A Stimulant?

Most people asking “is Lions mane a stimulant?”  are often afraid that takingLion's mane before bedcan make them lose sleep. The answer to the question "is Lion's mane a stimulant?" is a big NO. 

Lion’s mane is not a psychoactive substance.  The mushroom can be enjoyed without any risk of addiction. The bioactive compounds in the mushroom can, however, stimulate the growth of nerve cells aiding in memory, cognition, and repair. This nootropic mushroom also plays a role in boosting mood and improving sleep quality.

Final Thoughts

Lion’s mane is a distinctive mushroom with well-known neuronal benefits. Taking Lion’s mane pre workout has a plethora of benefits for athletes and fitness enthusiasts. 

Consistent use of Lion’s mane has shown to help with almost everything related to working out. The mushroom reduces fatigue, inflammation-associated tissue damage, and blood lipid levels which ultimately lead to an increase in muscle endurance and athletic performance. The mushroom has gained a stellar reputation amongst athletes due to these positive mental and physical outcomes.


  1. Komiya, Y., Nakamura, T., Ishii, M., Shimizu, K., Hiraki, E., Kawabata, F., Nakamura, M., Tatsumi, R., Ikeuchi, Y., & Mizunoya, W. (2019). Increase in muscle endurance in mice by dietary Yamabushitake mushroom (Hericium erinaceus) possibly via activation of PPARδ.Animal science journal = Nihon chikusan Gakkaiho,90(6), 781–789. (1)   
  2. Liu, J., DU, C., Wang, Y., & Yu, Z. (2015). Anti-fatigue activities of polysaccharides extracted fromHericium erinaceus.Experimental and therapeutic medicine,9(2), 483–487. (2) 
  3. Won-Sik Choi, Young-Sun Kim, Byeoung-Soo Park, Jang-Eok Kim & Sung-Eun Lee (2013) Hypolipidaemic Effect of Hericiumerinaceum Grown in Artemisiacapillaris on Obese Rats, Mycobiology, 41:2, 94-99, (3) 
  4. Lee, K. F., Chen, J. H., Teng, C. C., Shen, C. H., Hsieh, M. C., Lu, C. C., Lee, K. C., Lee, L. Y., Chen, W. P., Chen, C. C., Huang, W. S., & Kuo, H. C. (2014). Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine.International journal of molecular sciences,15(9), 15073–15089. (4) 
  5. Kushairi, N., Phan, C. W., Sabaratnam, V., David, P., & Naidu, M. (2019). Lion's Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia.Antioxidants (Basel, Switzerland),8(8), 261. (5)