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< class="article__title title benefits-of-cordyceps-for-kidneys-can-cordyceps-improve-kidney-disease"> Benefits Of Cordyceps For Kidneys: Can Cordyceps Improve Kidney Disease?>
Benefits Of Cordyceps For Kidneys: Can Cordyceps Improve Kidney Disease?
Oct 25, 22
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Author: Sony Sherpa

Benefits Of Cordyceps For Kidneys: Can Cordyceps Improve Kidney Disease?

  • by Sony Sherpa
  • |
  • 6 min read

The health of the kidneys is essential for general health and overall well-being. This is because the kidneys filter and eliminate waste products from the body and produce hormones that allow for proper bodily functions. 

The best way you can keep your kidneys healthy is to maintain an active, healthy lifestyle. A nutritious diet low in processed meats, salt, and other foods that harm the kidneys may also help lower the risk of kidney damage.

Many drugs used to treat kidney disorders, like mycophenolate (MMF) and cyclosporine, originated from mushrooms. Even traditional Chinese medicine uses medicinal mushrooms like Cordyceps for kidney health. It is believed that the fungus helps strengthen the kidneys.

Research has demonstrated that Cordyceps mushroom can replenish kidney health and improve chronic renal disease. This half caterpillar half mushroom can even protect the kidney from diabetes nephropathy.

So, let's explore Cordyceps and kidney disease and how the mushroom may help protect and strengthen the health of your kidneys.

Cordyceps For Chronic Kidney Disease

Cordyceps, also known as caterpillar fungus, is a herbal medicine commonly used in traditional medicine to treat various ailments, including chronic kidney disease (CKD).

Here's what we know about Cordyceps kidney disease benefits.

Cordyceps Sinensis Benefits

In a 2014 review published in the Cochrane database of systematic reviews(1), researchers evaluated the therapeutic effects of Cordyceps sinensis for treating people with CKD.

The paper included 22 studies that involved 1746 participants. Among people with CKD who were not receiving dialysis, Cordyceps preparations significantly decreased serum creatinine, increased creatinine clearance, and reduced protein in the urine over 24 hours.

Researchers concluded that Cordyceps, when used as an adjuvant therapy to conventional medicine, showed potential promise to increase creatine clearance, decrease serum creatinine, reduce proteinuria and alleviate complications associated with CKD.

Likewise, in another study published in the Urologia Internationalis(2) journal, scientists evaluated the effects of Cordyceps sinensis on renal functions in patients who underwent renal transplants and were suffering from chronic allograft nephropathy (CAN).

A total of 231 CAN patients who underwent transplantation and experienced chronic graft dysfunction were divided into two groups randomly. Patients in group A were treated with 2 grams of Cordyceps along with immunosuppressive agents, while patients in group B were treated with traditional immunosuppressive drugs only.

Blood urea nitrogen (BUN), serum creatinine, the amount of urinary protein in 24 hours, and the creatinine clearance rate of all patients were measured before and after treatment.

Six months of treatment with Cordyceps sinensis significantly improved serum creatinine and creatine clearance in group A. However, no significant improvement was observed for group B. Likewise, renal function improved in 72 patients and stabilized in 38 patients in the group receiving the mushroom.

Researchers concluded that Cordyceps sinensis therapy is advantageous in improving the renal function of CAN patients by retarding the progression of the disease.

In a Chinese study(3), researchers investigated 61 patients with lupus nephritis unresponsive to treatment with cyclophosphamide and corticosterone. When given for three years, Cordyceps powder protected kidney function, as measured by creatinine clearance. The results were significantly better than another traditional Chinese regimen that used Baoshekang and Tripterygiitotorium tablets.

Diabetic kidney disease (DKD) is the primary reason for CKD and leads to high mortality worldwide. The treatment of DKD is mainly focused on controlling hyperglycemia, high blood pressure, and proteins in the urine. However, this is insufficient and ineffective in delaying the progression of DKD.

Increasing scientific evidence(4) has identified the bioactive ingredients in Cordyceps sinensis, which can induce various effects on the treatment of DKD, such as anti-inflammatory, anti-hyperglycemia, and anti-oxidant activities.

The only drawback here is that Cordyceps sinensis is considered a very rare and expensive herb that is difficult to produce on a large scale. For this reason, several nutraceutical companies have opted to use Cordyceps militaris instead. The bioactive ingredients and effects of C. militaris and C. sinensis are pretty similar, and the former is a cheaper alternative to the latter.

Cordyceps Militaris Benefits

Cordyceps Militaris Benefits

Cordycepin in C. militaris has shown good promise in protecting against CKD. For example, in a 2019 study(5), cordycepin reduced urine protein, creatinine, and BUN levels after 3-month treatment. Similarly, another study published in 2016(6) found that Cordyceps militaris treatment preserves renal function in type 2 diabetic nephropathy in mice.


Is Cordyceps Good For Kidney?

Both Cordyceps sinensis and militaris have been shown to preserve renal function and protect against chronic kidney disease in both human and animal-based studies.

Who Should Not Take Cordyceps?

Those with bleeding disorders should avoid Cordyceps. Additionally, people taking anti-diabetic medications and blood thinners should not take the drugs with mushrooms.

Can I Take Cordyceps Every Day?

Yes, Cordyceps mushrooms are usually safe and well-tolerated by most people. However, speaking with a healthcare provider before using the mushroom daily is always good.

Final Thoughts

Several studies have explored the Cordyceps for kidneys benefits. The Himalayan mushroom can protect kidney function, lower protein excretion in the urine, and serum creatinine. If you suffer from kidney disease, talk to a health expert to start using this incredible mushroom.

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  1. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease, (1) 
  2. Effect of Cordyceps sinensis on Renal Function of Patients with Chronic Allograft Nephropathy, (2) 
  3. Study on effect of Cordyceps sinensis and artemisinin in preventing recurrence of lupus nephritis, (3) 
  4. Mechanism of Cordyceps sinensis and its Extracts in the Treatment of Diabetic Kidney Disease: A Review, (4) 
  5. Cordyceps militaris Improves Chronic Kidney Disease by Affecting TLR4/NF-κB Redox Signaling Pathway, (5) 
  6. Cordyceps militaris Treatment Preserves Renal Function in Type 2 Diabetic Nephropathy Mice, (6)

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