< class="article__title title"> How Long Does It Take For Lion’s Mane Mushroom To Work?>
How Long Does It Take For Lion’s Mane Mushroom To Work?
Jul 26, 22
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Author: Sony Sherpa

How Long Does It Take For Lion’s Mane Mushroom To Work?


If you're like most functional mushroom supplement users, you're probably always looking for ways to boost your brain power. You might have heard that the Lion's Mane mushroom can help improve cognitive function, memory and creativity. But how long does it take for Lion's Mane to work? And what are the best ways to take it? Keep reading to find out!

Natural supplements are getting increasingly popular as most of us are beginning to gravitate towards a healthy lifestyle. More and more people are turning to mushrooms like Lion's mane to boost their brain and overall health

Generally, like with all mushroom supplements, it takes a couple of weeks for the effects of Lion’s mane to kick in the body. The highly nutritive compounds in medicinal mushrooms take their time to have a beneficial impact on our health and well-being. The results have both.

This article here is going to explore how long for Lion's mane to work in the body. We will even dig deep into the research of the superfood mushroom to see if it really works.

How Long Does Lion's Mane Take To Work?

Mushroom enthusiasts, that are eager to use Lion’s mane mushroom, have one important question on their mind: Does lion's mane work immediately or does it take a while?

While the effects of the adaptogenic fungus cannot be seen immediately, the time it takes for Lion's mane mushroom depends on many factors. It differs according to induvial biochemistry and also on the dosage you are taking. However, there is a general timeframe within which you can expect to notice the effects of the mushroom.

The mushroom takes anywhere between 2 to 4 weeks for its effects to show up. The effects of Lion’s mane are not immediate and may take some time to show as the supplement needs to build up in your body. Some studies have had participants consume Lion’s mane extract for anywhere between 4 weeks to 4 months.

Now depending upon the desired effects, the time taken for the mushroom to work may also vary. For instance, some people have noticed that Lion’s mane mushroom decreased anxiety and increased mental clarity with just 2 to 5 of use. This of course depends on other factors like dosages too.

Does Lion's Mane Really Work?

With so many mushroom supplements available today, it is only natural to be skeptical. Many people ask us: do lion's mane supplements work? We will let the research speak for itself.

Research has found that Lion's mane mushrooms could protect against dementia. Animal studies(1) have shown that the mushroom displays various pharmacological activities that aid in the prevention of dementia in conditions such as Parkinson’s and Alzheimer’s disease.

It also reduces the symptoms of depression, anxiety as well as mood disorders.

Rat studies have found that Lion’s mane helps speed nervous system(2) injuries by 44%.

Test tube studies have found that extracts of Hericium erinaceus can help prevent the oxidation of cholesterol(3) in the blood which is implicated in several diseases of the heart and blood vessels.

In addition to these effects, Lion’s mane mushroom has also been shown to help reduce blood sugar(4), fight cancer cells(5), reduce inflammation(6), and boost the immune system(7).

While most of these studies have been done on animals, they hold great potential for humans too!

Does Lion's Mane Give You Energy?

Does Lion's Mane Give You Energy?

Lion's mane mushroom is a catalyst for the production of energy in our bodies. The fungus can give you an energy boost, and there are a few reasons(8) why.

First, it is packed with anti-oxidants. These not only support the overall health of the cells in our bodies, but it also removes harmful and unstable molecules in the body. Since energy transportation takes place at a cellular level, an anti-oxidant-rich diet will make it easier for the body to produce energy.

Second, Hericium erinaceus is known to decrease the levels of lactic acid(9) in the blood which may cause fatigue after intense physical activity. Lion's mane mushroom also enhances the glycogen content in the tissue which ultimately promotes energy production.

How Does Lion's Mane Make You Feel?

Lion's mane mushrooms make you feel good on every level. The mushroom is known to reduce the symptoms of anxiety(10) and depression as well as improve mood(11).

Lion's mane mushroom also provides spiritual and mental benefits. With consistent use of the fungus, Hericium erinaceus may be able to improve focus, clarity, and cognition.

Lion's mane is not a psychedelic mushroom and will not get you high. Instead, continued and consistent use of the fungus leads to a boost in mood and mental energy. There are also reports that the mushroom increases the sense of smell and depth perception. even more, few people have reported an improved ability to concentrate, make decisions, learn and solve problems.


How Long Should You Take Lion's Mane For?

Lion's mane mushrooms should be used consistently over at least 2 weeks to get the desired effects. It has been reported that the mushroom is possibly safe when used (in a dose of 1 grams daily) for 16 weeks.

How Often Should You Take Lion's Mane?

Lion's mane can be taken up to three times per day. Any frequency higher than this is not recommended currently. It is always better to speak with your healthcare provider regarding the best dosage for you, as the effects may depend on the result you are trying to achieve.

Final Thoughts

The effects of Lion’s mane mushroom are not immediate and you may need to wait till the mushroom build up in the body to see the effects. This may take anywhere between 2 weeks to several months. 

Have you tried lion’s mane? Let us know in the comments below how it worked for you. And if you’re looking for more information on this topic, be sure to check out our other blog posts about the benefits of lion’s mane mushroom. We have plenty of information and lions mane recipes to help get you started!


  1. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model, (1)
  2. Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine, (2)
  3. Inhibitory effect on in vitro LDL oxidation and HMG Co-A reductase activity of the liquid-liquid partitioned fractions of Hericium erinaceus (Bull.) Persoon (lion's mane mushroom), (3)
  4. Protective Effect of Ethanol Extracts of Hericium erinaceus on Alloxan-Induced Diabetic Neuropathic Pain in Rats, (4)
  5. Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells, (5) 
  6. Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine, (6)
  7. Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology,(7)
  8. Hericium erinaceus: an edible mushroom with medicinal values, (8)
  9. Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus, (9)
  10. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake, (10)
  11. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? (11)

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