< class="article__title title"> Detailed Guide To Turkey Tail Mushroom Dosage For Maximum Benefits>
Detailed Guide To Turkey Tail Mushroom Dosage For Maximum Benefits
Apr 05, 22
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Author: Sony Sherpa

Detailed Guide To Turkey Tail Mushroom Dosage For Maximum Benefits


Turkey tail, also known as Trametes Versicolor, cloud mushroom, or Kawaratake, is a medicinal mushroom that is loaded with health benefits.Turkey tail benefits have made it a popular holistic solution in traditional Chinese and western medicine for a host of ailments as well as to boost digestive health and immunity.

The fungus, named after its distinctive multicolored concentric bands of brown and tan, is rich in niacin, phosphorus, riboflavin, potassium, pantothenic acid, and copper. It is also packed with polysaccharide krestin (PSK), ergosterol, beta-glucans, and amino acids. Another peculiar aspect of the mushroom is that it helps the body to make vitamin D with even a tiny amount of sunlight.

The chemicals produced by the mushroom, either naturally or through a process of fermentation, have been found to have medicinal properties. The polysaccharide extract (PSK) has been approved as a pharmaceutical-grade medicine(1) in Japan. Owing to this, the Turkey tail has been utilized in the treatment of cancer for over 30 years. 

While the fungi products do offer people a better life with their numerous benefits, most people want to avoid the turkey tail side effects when using the mushroom. The key to avoiding the side effects of the mushroom while enjoying its benefits for the immune system and cancer patients is to use the right turkey tail mushroom dose. 

To ensure you are enjoying the turkey tail mushroom whole foods benefits, this article will explore the Turkey tail mushroom dosage recommended by physicians. We will break down the scientific research for you and give you the turkey tail dose so that you can benefit from this white-rot fungus.

What's even better is that we won't be just discussing one dosage for all conditions—we will give you specific dosage for the main conditions. For example, you will get to learn the turkey tail dosage for cancer, the best turkey tail mushroom for ulcerative colitis dosage, the turkey tail mushroom for dogs dosage, the best turkey tail mushroom capsules dosage, and much more.  

What Is The Right Turkey Tail Mushroom Dosage?

Although it is popularly used in cancer treatment, Turkey tail is also beneficial in maintaining good health. 

If you are wondering how much turkey tail mushroom should I take for general health, a daily dose of 2000 mg of turkey tail mushroom is the optimum dose (2) for maintaining premium health. This turkey tail dosage provides adequate mushroom bioactive compounds like beta-glucans that strengthen and balance the immune function of the body.

Some diseases and the turkey tail dosage for them are discussed below:

1. Turkey Tail Dosage For Cancer

Turkey tail mushroom plays a key role in the treatment of cancer.Turkey tail mushroom for cancer is part of the numerous ways people with cancer improve their lives. 

However, if you have not used the mushroom supplement or ingredients for cancer, you may wonder what is the ideal turkey tail mushroom cancer dosage. To help you understand how much turkey tail to take for cancer, we will take a deeper look at the variety of ways through which mushrooms turkey tail are used in various countries for the treatment of cancerous cells.  

 In Japan(3), turkey tail extract is available as a prescription product in the form of oral capsules. This contains 1 g of PSK that is taken thrice daily. This suggests that in Japan, the recommended turkey tail mushroom dosage for cancer is about 3 grams per day.

In China, it is also approved for use turkey tail mushrooms in the treatment of cancer. The oral capsules contain 1.08 g of mushroom extract given three times a day. This suggests that in China, when people are using the best turkey tail mushroom supplement to treat cancer, the answer to the question "how much turkey tail for cancer?" is about 3.24 grams per day. 

It is, however, worth noting that the turkey tail mushroom dose for cancer is not limited to between 3g and 3.24g per day. When using the best turkey tail supplement for cancer, research information shows the dosing may vary from one person to the other. Below, we will take a look at research studies that show how to consume turkey tail mushroom for different types of cancer. These dosages, however, may need to be adjusted for you specifically before you can add the mushroom to your diet to fight cancerous cells. 

Turkey tail mushroom has been used in clinical trials in women with breast cancer (4) after primary oncologic treatment.In patients with breast cancer improvements in immune status were observed with a daily dose of 9 grams. This turkey tail mushroom cancer dosage is safe and tolerable.

Many clinical trials have used Trametes versicolor in lung cancer(5) at a dose of 3 grams per day. This dose for turkey hill mushroom has been shown to improve immune function and hematological parameters like hemoglobin and white blood cell numbers. It was also associated with a decrease in symptoms related to the tumor. In patients with lung cancer, there was greater effectiveness of the treatment as opposed to when chemotherapy was used alone.

Turkey tail mushroom has been shown to prevent human papillomavirus (HPV) induced cancers of the oral cavity(6). The turkey tail mushroom dosage for HPV was two 200 mg capsules for 2 months. For patients with oral cancer, this dose was combined with another medicinal mushroom, Lion's mane.

2. Turkey Tail Dosage For Alzheimer's Disease

The powder of Trametes Versicolor was used in a dose of 200mg/kg for 30 days in animal models with Alzheimer's(7). This orally administered dose of Turkey tail protected against the neurodegenerative damage and inflammation caused due to Alzheimer's disease. 

The polysaccharides in Turkey tail mushrooms have immunomodulatory and antioxidant effects. These properties of the mushroom can be utilized in aging and related health concerns like Alzheimer's disease.

There is increasing evidence that supports the role of oxidative stress in Alzheimer's disease. The inflammation of the nerve cells caused by oxidative damage is an early change in the development of neurodegenerative disease.

Mushroom-derived chemicals like lipoxins can promote the resolution of inflammation. They act as a brake signal in the inflammatory process. In the present study, the expression of mushroom lipoxins was measured in the different parts of the brain, following the 30-day oral dose of Turkey tail.  Parts of the brain mainly involved in Alzheimer's disease showed an increased amount of lipoxins, indicating its neuroprotective role in the disease.

If you are wondering what is the best turkey tail supplement for Alzheimer's disease, you should know that all supplements do carry compounds and vitamins that help with the treatment of Alzheimer's. However, the levels of these compounds may vary from one species of mushroom to the other. It is recommended that you add an organic turkey tail to your food to enjoy the maximum performance when it comes to the restoration of mental energy and the treatment of Alzheimer's. 

3. Turkey Tail Dosage For Osteoporosis

Osteoporosis is a very common condition among elderly people. People with this condition often want to know how to take turkey tail mushroom to treat the condition. 

Turkey tail mushroom, when given orally at a dose of 100mg/kg for 28 days, was found to improve bone thickness and density(8) in rat models. The rats treated with Turkey tail showed maximal load-bearing capacity with increased bone thickness as compared to other rats that were not given the mushroom. 

In another study, Turkey tail improved bone loss in mouse models with breast cancer spread to the bones. 1g/kg of the mushroom extract was given orally for four weeks, which resulted in an increase in bone volume(9) by 10.3% as compared to the other study subject that did not receive the mushroom extract.

This study shows that Turkey tail mushroom reduces bone loss even when cancer has spread to the bone. This could be attributed to the fact that turkey tail mushroom prevents the breakdown and assimilation of the bone by inhibiting the cells (osteoclasts) that cause such effects. 

4. Turkey Tail Mushroom Pain Management Dosage

Turkey tail mushroom powders have been shown to reduce pain, similar to Aspirin. The analgesic effect of the mushroom was observed in rodent models receiving500 mg/kg of mushroom powder.

In this 2020 study from Taiwan(10), animal subjects were divided into four groups. The first group was not given Aspirin or mushroom extract; the second group received 500mg/kg of Turkey tail mushroom, and the third and fourth groups were given different doses of Aspirin.

Markers of pain and inflammation were measured, which were found to decrease significantly following the mushroom feeding. There is a high percentage (11.92%) of Oleanolic acid in Trametes Versicolor. This active compound was found to have analgesic effects that even effectively reduced physical pain triggered by hot plates.  

The polysaccharopeptides from the mushroom have also been found to reduce morphine-induced pain hypersensitivity(11)at a dose of 200 microgram/kg for 3 weeks.  The mushroom extract reduced the tolerance brought on by long-term administration of morphine, providing relief from osteoarthritis pain. 

5. Turkey Tail For Diabetes 

A 0.1g/kg oral dose of Turkey tail was found to reduce blood sugar levels(12) in animal models. This dose was also associated with a decline in insulin resistance(13) in another study.

Many preclinical studies have reported that the mushroom improves diabetes-related pathology. The 0.1g/kg oral dose of Trametes Versicolor decreased the blood sugar level after meals (postprandial glucose). They also decreased markers of oxidative stress and lipid levels that contribute to the development of diabetes.

A preparation containing 25 mg/kg (14)of Turkey tail mushroom also protected the heart from the side effects of diabetes. This dose of the mushroom reduced the symptoms of diabetic cardiomyopathy including inflammation and fibrosis. 

A four-week administration of polysaccharopeptides obtained from Turkey tail mushroom was found to lower blood sugar levels(15).  0.1, 0.5, or 1.0 g/kg of the mushroom extract were given to animal models. This dose was associated with an increased uptake of glucose by the cells, thereby ameliorating high blood sugar levels. 

Diabetes and obesity are very closely related—one of the risk factors for type 2 diabetes is higher than normal body weight. In addition to increasing your risk of diabetes, obesity also increases your risk of other conditions. The good news, however, is that turkey tail mushroom weight loss benefits can be enjoyed by taking the mushroom at the exact dosage for diabetes. 

6. Hearing Loss Turkey Tail Dosage 

Turkey tail mushroom has been used for neuro-protection in Meniere's disease(16). This is a disease of the middle ear characterized by hearing loss and spells of dizziness. 3 tablets of 500 mg of turkey tail were given twice a day for two months. This turkey tail dosage improved biochemical parameters used to assess the cellular response to the disease.

Inflammation of the neurons and oxidative stress play an important role in the development of Meniere's disease. Neuro-protection against the disease can be reinforced by exogenous nutritional supplements like Turkey tail mushroom. The present study highlighted the importance of the antioxidant and immunostimulatory action of Turkey tail in protecting against Meniere's disease. 

7. Turkey Tail Dosage for Dogs

While it is easy to assume that Turkey tail mushroom is only ideal for people, this is not the case. The numerousturkey tail mushroom benefits for dogs make the fungi ideal for man's favorite pet. When used by dogs, turkey tail boosts immunity, improves the health of the digestive tract, fights cancer, and does much more. 

However, before giving your dog turkey tail, you may want to know the best turkey tail mushroom dosage for dogs. The correct turkey tail mushroom dosage for dogs often depends on animal size and purpose for use. In most cases, amounts are calculated on a milligram (mg) per kilogram of the dog's weight basis. 

A dog weighing 30 kilograms should take a maximum of 3,000 mg (3 grams) of turkey tail mushroom daily. A small dog weighing just 10 kilograms will need 1,000 mg (1 gram) of turkey tail. This indicates that the ideal turkey tail dosage for dogs is 100 mg per kilogram of body weight. 

What Is The Best Time To Take Turkey Tail Mushroom

It is worth noting that the performance of the turkey tail mushroom is not affected by the time the mushroom is taken. The ideal time to take the mushroom is often affected by the reason behind taking the mushroom. 

For example, for people who need a bust of energy during their morning workout, taking the mushroom in the morning is a good idea. However, for people taking it to enjoy the turkey tail mushroom sleep benefits, the best time to take the mushroom is at night, just before going to bed. 

If you are asking yourself the question, "does turkey tail mushroom make you high?", chances are that you are worried the mushroom may affect your mood and performance if you take it in the morning. The good news, however, is that the mushroom does not make you high. 

If you are not sure about the best way to take turkey's tail mushroom, talking to a doctor can help you out. The doctor should help you find an ideal way to take the turkeytail mushrooms.    

How Long Does It Take For Turkey Tail Mushroom To Work?

How Long Does It Take For Turkey Tail Mushroom To Work?

If you are just starting on the functional mushroom, you may not experience immediate results. It takes time for your body to assimilate the bioactive compounds of the mushroom.  It may take up to three weeks for your body to experience the turkey tail mushroom benefits, during which it is recommended that you double up the 2000 mg dosage.

Final Thoughts

Turkey tails mushroom is a promising medicinal mushroom with many proven benefits. From boosting energy levels to improving brain and mental performance, turkey tails are one of the best foods. 

The general recommended Turkey tail dosage is 2g per day, which can be either consumed as capsules or powders. It is a safe and well-tolerated mushroom; however, it is always better to consult your physician or oncologist before use.  


  1. Medicinal Mushrooms (PDQ®)–Health Professional Version - National Cancer Institute. (2016, November 30). (1) 
  2. (PDF) A Turkey Tails Polysaccharide as an Immunochemotherapy Agent in Cancer. (n.d.). ResearchGate. (2) 
  3. Medicinal Mushrooms (PDQ®)–Health Professional Version - National Cancer Institute. (2016, November 30). (3) 
  4. Torkelson, C. J., Sweet, E., Martzen, M. R., Sasagawa, M., Wenner, C. A., Gay, J., Putiri, A., & Standish, L. J. (2012). Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer.ISRN Oncology,2012, 251632. (4) 
  5. Fritz, H., Kennedy, D. A., Ishii, M., Fergusson, D., Fernandes, R., Cooley, K., & Seely, D. (2015). Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer.Integrative Cancer Therapies,14(3), 201–211. (5) 
  6. Donatini B. (2014). Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial.International journal of medicinal mushrooms,16(5), 497–498. (6) 
  7. Trovato, A., Siracusa, R., Di Paola, R., Scuto, M., Fronte, V., Koverech, G., Luca, M., Serra, A., Toscano, M. A., Petralia, A., Cuzzocrea, S., & Calabrese, V. (2016). Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer’s disease pathogenesis.NeuroToxicology,53, 350–358. (7) 
  8. Chen, C.-H., Kang, L., Lo, H.-C., Hsu, T.-H., Lin, F.-Y., Lin, Y.-S., Wang, Z.-J., Chen, S.-T., & Shen, C.-L. (2015). Polysaccharides ofTrametes versicolor Improve Bone Properties in Diabetic Rats.Journal of Agricultural and Food Chemistry,63(42), 9232–9238. (8) 
  9. Riley D. (2012). Patient Perspective: An Interview.Global advances in health and medicine,1(5), 18–19. (9) 
  10. Hung, P.-H., Lin, C.-M., Tsai, J.-C., Hsu, T.-H., Chang, S.-L., Chen, Ying-I., & Tzeng, C.-Y. (2020). Acetylsalicylic acid-like analgesic effects of Trametes versicolor in Wistar rats.Biomedicine & Pharmacotherapy,129, 110328. (10) 
  11. Wang, K., Wang, Z., Cui, R., & Chu, H. (2019). Polysaccharopeptide from Trametes versicolor blocks inflammatory osteoarthritis pain-morphine tolerance effects via activating cannabinoid type 2 receptor.International Journal of Biological Macromolecules,126, 805–810. (11) 
  12. International Journal of Medicinal Mushrooms - Begell House Digital Library. (n.d.). (12) 
  13. Xian, H., Che, H., Qin, Y., Yang, F., Meng, S., Li, X., Bai, Y., & Wang, L. (2017). Coriolus versicolor aqueous extract ameliorates insulin resistance with PI3K/Akt and p38 MAPK signaling pathways involved in diabetic skeletal muscle.Phytotherapy Research,32(3), 551–560. (13) 
  14. Wang, Y., Li, H., Li, Y., Zhao, Y., Xiong, F., Liu, Y., Xue, H., Yang, Z., Ni, S., Sahil, A., Che, H., & Wang, L. (2019).Coriolus versicolor alleviates diabetic cardiomyopathy by inhibiting cardiac fibrosis and NLRP3 inflammasome activation.Phytotherapy Research,33(10), 2737–2748. (14) 
  15. Lo, H. C., Hsu, T. H., & Lee, C. H. (2020). Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus.International journal of medicinal mushrooms,22(5), 417–429. (15) 
  16. Scuto, M., Di Mauro, P., Ontario, M. L., Amato, C., Modafferi, S., Ciavardelli, D., Trovato Salinaro, A., Maiolino, L., & Calabrese, V. (2019). Nutritional Mushroom Treatment in Meniere's Disease with Coriolus versicolor: A Rationale for Therapeutic Intervention in Neuroinflammation and Antineurodegeneration.International journal of molecular sciences,21(1), 284. (16)