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Using Mushrooms For Adrenal Fatigue? Here’s Our Top Picks
Jul 20, 23
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Author: Sony Sherpa

Using Mushrooms For Adrenal Fatigue? Here’s Our Top Picks

  • by Sony Sherpa

    Medically reviewed by

    Sony Sherpa

    Dr. Sony Sherpa is a board-certified Clinical Doctor and dedicated advocate for holistic medicine, specializing in functional mushrooms. Her blend of medical expertise and passion for alternative wellness lends authenticity to her role as a contributor for Natures Rise.

  • |
  • 11 min read
Using Mushrooms For Adrenal Fatigue? Here’s Our Top Picks

Medicinal mushrooms have been utilized for centuries in traditional Eastern medicine to improve overall health and well-being. Modern science has revealed that these ancient medicines are incredibly effective allies in boosting energy levels and reducing stress.

But are mushrooms good for adrenal fatigue? Mushrooms play an essential function in adrenal health. They are exceptionally high in the polysaccharide beta-glucan, which has been found to reduce stress and healthy cortisol levels and improve immune system performance.

They can also help boost energy production, enhance digestion and nutrient absorption, and restore hormonal balance. Because of these qualities, they are essential for persons suffering from adrenal exhaustion.

Let’s review the top mushrooms for adrenal fatigue.

Understanding Adrenal Fatigue

Understanding Adrenal Fatigue

Adrenal exhaustion is a disorder brought on by continuous stress. It is distinguished by symptoms such as weariness, anxiety, difficulty sleeping, etc. The adrenal glands create hormones that control the body's stress response.

When these glands get overworked due to extreme or persistent stress, they cannot generate adequate hormones to maintain the body in balance.

Long-term stress causes the adrenal glands to produce more and more stress hormone cortisol until they are overworked and unable to keep up. This might result in various symptoms, such as physical exhaustion, brain fog, increased worry,  weight gain, and difficulty sleeping.

Adrenal exhaustion is not recognized medically. It's a colloquial name for a group of symptoms. Because these symptoms are vague, they might be caused by various illnesses or ailments. As a result, it's difficult to classify adrenal exhaustion as a medical illness.

According to research, there is no link between adrenal dysfunction and nonspecific fatigue. However, some doctors feel that continuous stress can affect your body's ability to regulate hormones appropriately. This imbalance may cause a variety of symptoms, including weariness and worry.

As a result, while adrenal fatigue is not a biological ailment, it affects many people. It is critical to consult your doctor if you suffer from persistent weariness and anxiety. They can help in determining the best treatment for your problems.

The Role Of Mushrooms In Adrenal Health

The Role Of Mushrooms In Adrenal Health

Adaptogens, also known as adaptogenic herbs, are a class of botanicals (including some mushrooms) that help the body's inherent ability to adapt to physical and emotional stress.

Adaptogenic herbs, also known as adrenal adaptogens, have been used for hundreds of years in many herbal traditions. Ayurvedic heritage in India includes Holy Basil, Ashwagandha, Amla, and Shilajit. Folk herbalists in Russia relied on Rhodiola and Rhaponticum. Traditional Chinese herbalism employs Schisandra, Asian Ginseng, and mushrooms that we'll go into in detail later: Cordyceps, Turkey tail, Maitake, Chaga, Lion’s mane, and Reishi are all medicinal mushrooms.

Adaptogens have been proven in studies(1) to help with adrenal exhaustion in a variety of ways, such as:

  • Adaptogens can improve adrenal gland secretion efficiency, preventing excessive cortisol production.
  • Adaptogens can speed up the breakdown of cortisol into inactive molecules.
  • Adaptogens can "prevent oxidative damages, increase cellular energy levels leading to the maintenance of normal adrenal function."

Reishi, Chaga, and Cordyceps mushrooms are examples of apoptogenic functional mushrooms with various health advantages. These mushrooms help a balanced response to occasional physical or emotional stress, mental attention and focus, stamina, energy, and endurance. Furthermore, they promote optimal energy levels regularly and for athletes.

Mushrooms For Adrenal Support

Here are the top mushrooms for adrenal fatigue:



Cordyceps (Cordyceps militaris) is a highly regarded traditional Chinese herbal medicine herb. In China, it is known as a sexual tonic and is frequently used to sustain a healthy libido in older adults.

Cordyceps also help our bodies respond to stress, boost cellular vitality and endurance, and support the body's natural metabolic systems.

This mushroom contains glycoproteins, polysaccharides, and cordycepin, which help reduce inflammation, strengthen immunity, and improve energy levels and may be associated with Cordyceps adrenal fatigue benefits. Studies(2) have also revealed that it can protect against stress-related issues like anxiety and depression.



Chaga is a potent fungus that helps increase energy levels and reduce stress by harmonizing hormones and supporting the body's natural healing processes. It has anti-inflammatory(3) and anti-viral qualities, making it effective in the treatment of a variety of illnesses.

Chaga, as an adaptogen, aids the body's adaptation to stimuli by regulating hormones such as cortisol levels. This aids in reducing adrenal exhaustion symptoms such as fatigue, irritability, and insomnia.

By encouraging healthy bacteria balance in the gut and boosting circulation, Chaga also benefits systems throughout the body, including the digestive and cardiovascular systems. It can be consumed as a tincture or tea to nourish and energize the body.

Chaga contains a high concentration of B vitamins, iron, calcium, zinc, and other minerals. It is also high in antioxidants, which can help protect the body from free radical damage.

This is a very potent medicinal mushroom that should be handled with caution. Before incorporating Chaga into your daily regimen, consult with your doctor.



The 10,000-year mushroom (Ganoderma lucidum) is also known as the mushroom of immortality or the fungus of immortality. Reishi(4) is prized for its adaptogenic characteristics and assistance for overall wellness, relaxation, and immunity.

Reishi may also help with stamina and energy levels. It also promotes relaxation and the body's ability to adapt to temporary stress.

So, why pick Reishi mushrooms for adrenal fatigue?

Reishi is a beautiful alternative for people suffering from adrenal exhaustion because it reduces stress and increases the body's natural energy levels. It contains potent antioxidants and substances that may help in the reduction of inflammation and the regulation of hormone levels. It also promotes good blood sugar balance, essential for battling fatigue.

Turkey Tail

Turkey Tail

Turkey tail mushroom is a medicinal mushroom having anti-inflammatory and immune-boosting properties(5). It contains compounds that have been shown to protect the body from stress, exhaustion, and other effects of adrenal fatigue.

Turkey tail may also help with inflammation, immunity, and digestion. It is high in critical vitamins and minerals like calcium, B vitamins, and magnesium. These nutrients can assist in maintaining healthy hormone levels while increasing serotonin and dopamine production.

Lion's mane

Lion's mane

Lion's mane is a medicinal mushroom with potent brain-boosting properties. Traditional Chinese medicine has utilized it to help improve cognitive function, such as focus and memory.

Compounds in this mushroom have been proven to help protect nerve cells, enhance neuron growth, and reduce inflammation in the brain. It also contains a high concentration of hericenones, which are thought to increase the body's Nerve Growth Factor (NGF)(6) production.

This makes it an extremely effective treatment for patients suffering from adrenal fatigue, as NGF aids in healing adrenal gland damage.

According to research, Lion's mane may help reduce weariness, raise energy levels, and improve mental clarity. This mushroom is known for its immune-modulating characteristics, which can aid persons suffering from adrenal exhaustion, and its brain-boosting properties. It reduces inflammation and improves the body's ability to fight infection and disease.



Another medicinal fungus used to alleviate adrenal fatigue is Maitake. It contains beta-glucans, which have anti-inflammatory and immune-modulating properties.

This can help individuals suffering from adrenal exhaustion by reducing inflammation and improving the body's ability to fight infection and disease. Studies have also shown Maitake to help relieve stress and increase mental clarity.

Incorporating Mushrooms Into Your Routine

Incorporating Mushrooms Into Your Routine

Including mushrooms in our daily lives can appear to be a daunting task. On the other hand, finding simple and quick ways to include them in our routine does not have to be complicated.

Here are three simple and delicious ways to consume functional mushroom supplements.

1. Take mushroom powders with your morning coffee, or add them to savory meals, smoothies, or teas.

2. Pop a pill on the go.

3. Place the tinctures under the tongue or in a cup of tea.

There isn't much information on the optimum dosage and best times to take functional mushroom supplements. Because everyone is different, start with the recommended dose and see how you feel. Before incorporating any new supplements into your routine, consulting with a health professional or physician is also a good idea.

FAQs About Mushrooms For Adrenal Fatigue

Can I Combine Different Types Of Mushrooms For Adrenal Fatigue Support?

You both can and should. Mushrooms, when combined or "stacked," have a synergistic effect on your body and mind. Each mushroom adds a distinct flavor to each combination.

How Long Does It Take To See Benefits From Mushrooms For Adrenal Fatigue?

It takes time for your body to adjust to the new supplement when taking functional mushrooms. The mushroom supplements support your body's optimal functioning over time, usually after two to three weeks. However, for some, you may experience the benefit in less time.

Are There Any Contraindications Or Precautions Associated With Mushroom Use For Adrenal Fatigue?

Dry mouth, itching, dizziness, nausea, stomach upset, and rash can all be caused by mushrooms. To be safe, avoid using if you have a bleeding disorder, are pregnant, or are breastfeeding.

Key Takeaways

Functional mushrooms are widely loved for their immune system benefits, but as more study is conducted, scientists are discovering more and more benefits. Even though the phrase "adrenal fatigue" is a disputed diagnosis with little evidence to back it up, the symptoms that can appear due to excessive stress are genuine. It indicates that the adaptogenic properties of Reishi, Turkey tail, Chaga, Lion's mane, Maiatke, and Cordyceps, the essential mushrooms for adrenal fatigue, can be particularly effective in coping with symptoms linked with decreased adrenal functioning, as well as in preventing these symptoms.

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  1. A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide, (1) 
  2. Antidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal model (2) 
  3. The Anti-Inflammatory Properties of Chaga Extracts Obtained by Different Extraction Methods against LPS-Induced RAW 264.7, (3) 
  4. Evaluation of Antianxiety Potential of Four Ganoderma (Agaricomycetes) Species from India in Mice, (4) 
  5. Immunomodulatory Properties ofCoriolus versicolor: The Role of Polysaccharopeptide, (5) 
  6. Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells, (6)

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